Many people seek to purchase static injection of human immunoglobulin doctors: can enhance immunity, but not specifically for the new crown

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“Where can I get immunoglobulin?” Following the explosion of the sales of Lianhua Qingdai and blood oxygen meter, the frequent appearance of information seeking “immunoglobulin” on major social media platforms recently has aroused concern. A family member of a critically ill patient said on a personal social media platform that a doctor suggested buying immunoglobulin and contacted a pharmaceutical company to buy it only to find out that there was a shortage. According to the videos posted on social media platforms by people in many places, in addition to Wuhan, the “request for immunoglobulin” also occurred in Hubei Huanggang City, Henan and other places.

“The company’s main business is to provide a wide range of products and services to the public. On December 29, a citizen of Wuhan told reporters that in order to let the hospitalized father-in-law and grandmother with the drug, his family went to the pharmaceutical company early in the morning a few days ago to line up. “Each person is limited to buy 2 bottles, no premium, a bottle in about 500 yuan.” The citizen said that morning to his father-in-law and grandmother on the drug, is not yet discharged from the hospital, need to take care of.

The reporter contacted a number of pharmacies near the Union Hospital affiliated with the Tongji Medical College of Huazhong University of Science and Technology to learn that the current static injection human immunoglobulin has been out of stock for a period of time, and the next do not know when the goods will be available. One of the pharmacies said that the goods may be available after New Year’s Day, but the specific situation depends on the pharmaceutical company. The reporter then called a number of pharmaceutical companies in Wuhan to inquire about the situation, but did not get a clear response.

Pailin Biological (000403.SZ) said on December 23 in the investor interactive platform, the company’s production of static injection of human immunoglobulin has the ability to enhance the body’s resistance to infection and improve immunity function, has been included in the new crown pneumonia treatment-related drugs recommended list by Guangdong Province.

So can immunoglobulin injection prevent or treat New Guan? The reporter consulted with the attending physician of the Department of Infection of Zhejiang Provincial People’s Hospital as a patient, who said that the sedative injection of human immunoglobulin is medically referred to as propylenol, and that immunoglobulin can enhance immunity, but not specifically for new crown, and has no preventive effect, to prevent infectious diseases or vaccination. And ordinary and light type of new crown patients simply do not use the Propecia ball, do not need to hoard. “Generally some immune diseases will use the immunoglobulin, or serious infections, inflammatory factors storm.”

Liu Fang, deputy director of the Department of Hematology at Chengdu BOH, introduced on the public platform that propyl globulin is an immunoglobulin extracted from healthy human plasma, which neutralizes pathogens through antigen-antibody binding (passive immunity) and has a broad spectrum of anti-pathogenic bacterial infections. However, the half-life of propecia globules in the body is only about 2 weeks, so it is difficult to achieve a strong and long-lasting effect with a single low-dose (2-4 injections of 5-10 g at a time).

High-valence immunoglobulins for pathogenesis, with clear anti-infective effects in large quantities for short-term input, are more mature, such as cytomegalovirus (CMV) immunoglobulins, hepatitis B immunoglobulins, tetanus immunoglobulins, and herpes zoster immunoglobulins.

Liu Fang said that plasma extracted from recovered persons for the treatment of patients in infection also refers to this principle, but the concentration of specific immunoglobulins in plasma is limited, and last year the BMJ (British Medical Journal) published the results of an evidence-based controlled study that proved that plasma from recovered persons is ineffective, probably because of insufficient potency. It would be more effective if potent immunoglobulins could be concentrated from the plasma of recovered individuals. “Hopefully, specific immunoglobulins for the new crown will be available soon. But no matter what, don’t treat blood products as health products.” Liu Fang said.